Advancements in spatial proteomics enable detailed tissue mapping, linking protein localization to disease mechanisms and ...

A protein located in the wrong part of a cell can contribute to several diseases, such as Alzheimer's, cystic fibrosis, and cancer. But there are about 70,000 different proteins and protein variants ...

Just like workers need the right environment to efficiently perform their tasks, proteins require placement within specific cellular compartments to function properly. Therefore, understanding where ...

In this article, we examine how multiomics is advancing disease research, particularly in neurodegenerative disorders such as ...

For the first time, researchers have directly visualized how newly formed cellular organelles leave the endoplasmic reticulum ...

Knowing which lysosomal proteins are enriched in which brain cell types will help better understand contribution to neurological disorders.

Adaptor protein (AP) complexes play central roles in intracellular vesicular trafficking by coupling cargo selection to ...

Researchers developed a new machine learning method that, given a relevant amino acid sequence, can automatically predict the location of a protein in any human cell line down to the single-cell level ...