Intricate molecular machineries, such as the ESCRT protein complexes, are well known for their ability to cut biological membranes. The discovery that membranes can also be severed by phase-separated ...
With an increasingly profound understanding of the interplay between condensate biology and diseases, there is a poised acceleration of classical drug development processes, catalyzing breakthroughs ...
A research group has developed a novel and highly accessible technology for producing uniform biomolecular condensates using a simple, low-cost vibration platform. The study is published in the ...
Cells use phase separation to organize their inner environment, creating compartments for essential biochemical reactions without the use of membranes. Tian's team realized that by engineering similar ...
A research group led by Professor Hiroaki SUZUKI and Takeshi HAYAKAWA from the Faculty of Science and Engineering at Chuo University, graduate student Zhitai HUANG, graduate students Kanji KANEKO (at ...
Protein aggregates, damaged organelles, and invading bacteria are identified and removed in healthy cells. An international ...
First-in-class condensate-modulating small molecule Development Candidate targeting pathogenic TDP-43 condensates.Restores global TDP-43 splicing ...
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Holographic precision, super-resolution vision: Scientists reveal hidden world of vital cellular structures
A team of NYU chemists and physicists are using cutting-edge tools—holographic microscopy and super-resolution imaging—to unlock how cells build and grow tiny, dynamic droplets known as biomolecular ...
Dewpoint to create a large-scale condensate phenomics atlas to illuminate cellular drivers of HPV-associated diseasesFunded by the Gates ...
BUFFALO, N.Y. — RNA has been in the limelight for its starring role in cutting-edge vaccine technology, but RNA molecules are also key players in the inner workings of cells. This lesser explored RNA ...
(Top) Schematic diagram of the basic unit (Y-motif) of DNA condensates and their binding via sticky-end interaction. (Bottom) A schematic diagram illustrates how DNA condensate formation is regulated ...
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