The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

Coagulation testing methodologies are often challenging for new users to understand. Terminology may be confusing and the methodologies are sensitive to many variables. Consideration of biological, ...

When the body experiences an injury to a blood vessel, muscular response to the injury causes the vessel to constrict, decreasing blood flow to the area. The blood is exposed to collagen in the ...

When injured, endothelial cells permit granulocytes and plasma constituents to enter inflamed tissue, which may lead to organ damage. Endothelial cell inflammation causes vasodilation through the ...

Studies by researchers at Columbia University Irving Medical Center suggest that one of the immune system’s oldest branches, the complement system, and coagulation dysfunction, may be influencing the ...