This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
AZoLifeSciences on MSN
Deep learning–based codon optimization framework boosts protein expression in E coli
By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...
The code of life is simple. Four genetic letters arranged in triplets—called codons—encode amino acids. These are the building blocks of proteins, the machinery that powers life. But the genetic code ...
AZoLifeSciences on MSN
Giant virus uses unique codon strategy to optimize host resource usage
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results