HCM is a genetic disease, usually caused by mutations in sarcomere proteins such as myosin, actin, tropomyosin, and myosin-binding protein C.

Beta-blockers have been the initial treatment for symptomatic obstructive hypertrophic cardiomyopathy (HCM) despite limited evidence of their efficacy. Aficamten is a cardiac myosin inhibitor that ...

Hypertrophic cardiomyopathy (HCM) is a genetic condition that can affect the structure and function of the heart. However, people with HCM can typically expect to live a relatively typical life. HCM ...