Several loci responsible for a familial KTCN have been mapped, including 16q22.3–q23.1 (KTCN2; MIM 608932), 16 3p14-q13 (KTCN3; MIM 608586), 17 2p24 (KTCN4; MIM 609271), 18 1p36.23-36.21, 19 ...
Genetic variation due to DNA mutation is a driving force of adaptation and evolution, as well as a contributing factor to disease. However, the mechanisms governing DNA mutation rate are not well ...
Since coronavirus disease 2019 (COVID-19) first arose, it has spread to nearly every country worldwide, and many governments were forced to enact costly and restrictive measures to limit the spread of ...
Many high-throughput experimental technologies have been developed to assess the effects of large numbers of mutations (variation) on phenotypes. However, designing functional assays for these methods ...
The order of cancer-driving mutations—genetic changes—plays an important role in whether tumors in the intestine can develop, new research reveals. Subscribe to our newsletter for the latest sci-tech ...