One of the hallmarks of Alzheimer's disease is the clumping of proteins called Tau, which form tangled fibrils in the brain.
MIT chemists used NMR spectroscopy to reveal the disordered “fuzzy coat” surrounding Tau protein fibrils, offering new ...
Fully open source model accurately predicts the 3D structures of proteins and biomolecules in silico, and serves as a foundational model for next generation of cutting-edge Protein AI tools The ...
CAMBRIDGE, MA – A protein located in the wrong part of a cell can contribute to several diseases, such as Alzheimer’s, cystic fibrosis, and cancer. But there are about 70,000 different proteins and ...
The blood-brain and blood-retinal barriers are protective systems that prevent harmful substances from entering the brain and ...
In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...
8don MSN
Boosting the cell's own cleanup: New class of small molecules accelerate natural protein degradation
Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...
The result is one molecule that can be both a checkpoint degrader and a cancer vaccine ( Nature 2026, DOI: 10.1038/s41586-025 ...
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