The reaction involves adding an organolithium anion to a source of a nitrogen-containing carbon stereocenter. This chemistry builds a crucial chiral center in verubecestat, a compound Merck has ...

Researchers have developed a new process that uses microwave flow reaction and recyclable solid catalysts to efficiently hydrolyze polysaccharides into simple sugars. The developed device utilizes a ...

Organic chemists optimizing a reaction, like chefs perfecting a dish, execute a single transformation over and over, each time tweaking a specific aspect, such as temperature or ingredient ratio, ...