A man accused in a St. Clair County murder case in October who reportedly fled across state lines to St. Louis is now behind ...

Bet365 Missouri offers a $365 bonus with the bet365 bonus code CBSBET365 for the Missouri sports betting launch ...

Homer G. Phillips Hospital opened its doors in, Missouri, in 1937. It was the first teaching hospital west of the Mississippi ...

The St. Louis Board of Aldermen opened the application process for hiring an “interim” St. Louis City Sheriff on Friday, a ...

St. Louis tends to draw in the biggest crowds of tourists to Missouri, but not far from that famous city is a charming town ...

ST. LOUIS — St. Louis lawmakers are taking on the mayor in the now three-way fight over who gets to appoint a replacement for ...

A St. Louis man died late Friday night after a crash in West Alton, according to the Missouri State Highway Patrol.

The Missouri women’s basketball team will finish 2-0 in nonconference road games this season following Sunday afternoon’s ...

The full height of that ceiling was on display in St. Louis last night. Not just offensively, but defensively as well. The ...

ST. CHARLES COUNTY, Mo. — A 52-year-old St. Louis man is dead after a one-vehicle crash in St. Charles County, according to ...

Saint Charles, Missouri, teams up with the local food bank to seek donations for needy families during the holidays.

Missouri lowers flags for a St. Charles paramedic, Lt. Sarah McCarthy, posthumously honoring her 23 years of service.