snmjournals.org

Somatostatin Receptor Imaging and Theranostics: Current Practice and Future Prospects

A new era of precision diagnostics and therapy for patients with neuroendocrine neoplasms began with the approval of somatostatin receptor (SSTR) radiopharmaceuticals for PET imaging followed by ...
snmjournals.org

Intraprostatic Tumor Segmentation on PSMA PET Images in Patients with Primary Prostate Cancer with a Convolutional Neural Network

Accurate delineation of the intraprostatic gross tumor volume (GTV) is a prerequisite for treatment approaches in patients with primary prostate cancer (PCa). Prostate-specific membrane antigen PET ...
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MRI-Guided Motion-Corrected PET Image Reconstruction for Cardiac PET/MRI

Simultaneous PET/MRI has shown potential for the comprehensive assessment of myocardial health from a single examination. Furthermore, MRI-derived respiratory motion information, when incorporated ...
snmjournals.org

Imaging Calreticulin for Early Detection of Immunogenic Cell Death During Anticancer Treatment

Surface-exposed calreticulin (ecto-CRT) is a well-known “eat-me” signal exhibited by dying cells that contributes to their recognition and destruction by the immune system. We assessed the use of a ...
snmjournals.org

Molecular Imaging of Neuroendocrine Prostate Cancer by Targeting Delta-Like Ligand 3

Treatment-induced neuroendocrine prostate cancer (NEPC) is a lethal subtype of castration-resistant prostate cancer. Using the 89Zr-labeled delta-like ligand 3 (DLL3) targeting antibody SC16 ...
snmjournals.org

Nectin-4–Targeted Radiotheranostics for Personalized Cancer Therapy: A Systematic Review

Journal of Nuclear Medicine December 2025, jnumed.125.271103; DOI: https://doi.org/10.2967/jnumed.125.271103 ...
snmjournals.org

A Fully Automatic Technique for Precise Localization and Quantification of Amyloid-β PET Scans

To quantify the aggregation of brain amyloid-β (Aβ) in vivo, different Aβ tracers have been developed for PET imaging techniques, with both clinical and research applications. Aβ PET scans can be ...
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Targeted Fluorescence Imaging of Bevacizumab-800CW in Patients with Neovascular Age-Related Macular Degeneration

Journal of Nuclear Medicine December 2025, jnumed.125.270802; DOI: https://doi.org/10.2967/jnumed.125.270802 ...
snmjournals.org

Combination Radiopharmaceutical Therapy and Radiotherapy for Thyroid Cancer: Dosimetry-Driven Precision Medicine

Journal of Nuclear Medicine December 2025, jnumed.120.253443; DOI: https://doi.org/10.2967/jnumed.120.253443 ...
snmjournals.org

Total-Body PET: Will It Change Science and Practice?

Total-body (TB) PET scanners with an axial field of view (AFOV) of at least 60 cm can image dynamic radiopharmaceutical distributions in the whole body. Although the benefits of the fine temporal ...
snmjournals.org

Radioimmunotherapy: From Current Clinical Success to Future Industrial Breakthrough?

patients or as consolidation after induction chemotherapy in front-line treatment in follicular lymphoma patients (1,2). Numerous publications have also reported promising efficacy of anti-CD20 ...
snmjournals.org

Trends in Nuclear Medicine in Developing Countries

This article describes trends in nuclear medicine in the developing world as noted by nuclear medicine professionals at the International Atomic Energy Agency (IAEA). The trends identified are based ...