One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...

Researchers at the CNIO show that oestrogens regulate gene expression by changing DNA supercoiling. Hormone-activated ...

Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose ...

Scientists depicted the four-dimensional genome model to reveal how DNA folding regulates genes. The discovery helps ...

Microscopy image showing the concentric pattern of F-actin, which gives rise to the clockwise rotation of the nucleus ...

Researchers created the most detailed maps yet of the genome’s three-dimensional organization using human stem cells and ...