A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

DNA- and RNA-binding proteins (DRBPs) constitute a significant fraction of cellular proteins and have important roles in cells. Their functions include control of transcription and translation, DNA ...

The researchers focused on the structure and dynamics of kinetoplast DNA, the mitochondrial genome of Trypanosomes, with an experimental study led by Edinburgh and a computational analysis that ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.

Inside cells, DNA twists and coils itself into a variety of different secondary structures—including i-motifs (iMs) and ...