One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

In diagrams and illustrations of cells, DNA is sometimes shown as a mass in the cell's nucleus, like a bowl of ramen noodles. For many years, it's been standard practice to take images of cells that ...

Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.

Researchers at the CNIO show that oestrogens regulate gene expression by changing DNA supercoiling. Hormone-activated ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

In an era where the U.S. healthcare system spends $4.5T annually yet faces systemic failures, with life expectancy plummeting to a three-decade low and chronic disease rates at an all-time high, the ...

Researchers have identified how the architecture of the cell nucleus can change gene activity in plants. This discovery reveals fundamental knowledge about genome regulation and points towards future ...