One area in which the backup-heavy 49ers struggled early in the season was the run game. McCaffrey averaged fewer than three yards per carry through the first few weeks and couldn’t break any big gains. The offense had to lean on him as a pass catcher, not as a runner.

Brock Purdy threw for 303 yards and three touchdowns as San Francisco is now one win away from earning the NFC's top seed.

San Francisco star tight end George Kittle will miss the 49ers' key game in playoff positioning on Sunday night against the Chicago Bears with an ankle injury.

Jennings hauled in a pass from Brock Purdy and ran it in for a 38-yard touchdown catch with 3:07 left in the fourth quarter on Sunday, which ended up being the game-winning score for the 49ers when they held the Bears out of the end zone on the final play to pull off a 42-38 win.

Caleb Williams and the Chicago Bears continue to pull off improbable wins, and they have a chance to clinch the NFC North in Week 17 against the San Francisco 4

The battle for the NFC West title and the No. 1 seed in the NFC between the Seattle Seahawks and San Francisco 49ers will be at 5 p.m. on Saturday night, the NFL announced.

The San Francisco 49ers received tough news on tight end George Kittle for Sunday's game against the Chicago Bears.

The NFL season rolls on Week 17 when the San Francisco 49ers host the Chicago Bears on Sunday Night Football. Time, how to watch, stream and schedule.

Simply, Chicago and San Francisco are two of the best teams in the land. They proved as much on Sunday night, combining to craft the league's best game thus far. The 49ers notched a 42-38 win over their in-conference rival, with Brock Purdy coming to life for the second-straight week.