Following the successful completion of the NHS national pilot in April 2025, the highly anticipated first results assessing CYP2C19 genetic testing to guide clopidogrel use in ischaemic stroke and TIA ...

The optimism is not unfounded. In specific, well-defined clinical scenarios, polygenic scores are beginning to demonstrate some tangible utility. For cardiovascular disease, MI-GENES, a 10-year follow ...

A patient arriving in A&E or another clinical setting, with suspected or known infection and the risk of sepsis, requires immediate action. Antibiotic admission more than one hour after suspected ...

The sepsis definition describes three elements: infection, the host response and life-threatening organ dysfunction. Diagnosis is made based on myriad signs and symptoms, and although infection ...

Sepsis is a critical global healthcare challenge, marked by complex and rapidly evolving symptoms, which can escalate with alarming speed leading to multi-organ failure. This leaves only a narrow ...

Prof Ahmed is a distinguished public health physician, epidemiologist, and global health diplomat with over three decades of experience spanning clinical medicine, academia, and public health policy ...

The BMJ reviewed research on health test kits sold in UK supermarkets and uncovered some deeply concerning gaps. Unlike routine diagnostic tests and assays used in clinical practice and prescribed ...

Cost-utility studies provide critical information for the costs and benefits of using any new test, typically building on existing public health and screening programmes, within a defined population.

The Wellcome Trust recently announced that they are funding a research programme to investigate synthetic human genomes, and Laura Blackburn, PHG Foundation’s Head of Science, had the opportunity to ...

CAR-T is a powerful tool which is still evolving. Here we highlight what is new in CAR-T cell therapy Cancer cells often play hide-and-seek with the immune system in an attempt to evade catastrophic ...

The GenomeIndia Project, launched in 2020, represents a strategic effort to map India’s vast genetic diversity. It focuses on India’s rich tapestry of ethnolinguistic communities (Indo-European, ...

It is no secret that the AI regulatory landscape has experienced monumental shifts in the last six months. Rhetoric that views regulation as a barrier to AI innovation and the cross-sectoral ...