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  1. Lucas Lab

    The laboratory of Dr. Carrie Lucas strives to discover mechanisms of disease driving rare immune disorders, focusing on the genetic, cellular, and biochemical underpinnings that can illuminate …

  2. Overall Focus — Lucas Lab

    The Lucas Lab's research interests build from our discoveries investigating new and suspected human inborn errors of immunity, which are rare and early-onset immune diseases caused by single-gene …

  3. All Publications — Lucas Lab

    Lucas CL, Workman CJ, Beyaz S, LoCascio S, Zhao G, Vignali DAA, and Sykes M. (2011). LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T cell tolerance …

  4. Projects and Tools — Lucas Lab

    We could recapitulate these immune defects in PI3Kgamma knockout mice using ‘dirty’ mouse models in which we expose laboratory mice kept in a clean research environment to ‘dirty’ mice exposed to …

  5. THE TEAM — Lucas Lab

    The Lucas laboratory is devoted to discovering new and translationally relevant principles of immunology by defining and studying severe pediatric immune disorders.

  6. News — Lucas Lab

    Jul 3, 2017 · Lucas Lab publishes its first paper in JACI! Lab Member Andrew Takeda under the guidance of Carrie Lucas has submitted their paper "Novel PIK3CD mutations affecting N-terminal …

  7. Opportunities — Lucas Lab

    Below is a list of examples of current positions that make up the Lucas Lab. If you feel like you are a good fit for the Lucas Lab, please visit our contact page to inquire!

  8. Funding — Lucas Lab

    Lucas Lab Past Funding We would also like to recognize those who have provided funding for the lab in the past!

  9. Contact — Lucas Lab

    Email Inquiries about Lab Positions Carrie Lucas (Principal Investigator) [email protected] Mailing Address The Anlyan Center (TAC) Building 300 Cedar Street Suite S640 New Haven, CT 06519

  10. Genomics Study — Lucas Lab

    what we do for this study The goal of this study is to to conduct high-impact immunology research with direct relevance to human health. This research provides insight into the mechanisms that cause …